WebCTD数据库(Comparative Toxicogenomics Database)整合大量化学物质、基因、功能表型和疾病之间相互作用数据,为疾病相关环境暴露因素及药物潜在作用机制研究提供极大 … WebComparative Toxicogenomics Database (CTD) •A freely available database that is dedicated to promoting the ... Chemical-gene interactions Gene-disease associations Inference score 2.28 16.21 63.70. 14.04. Chemical-pathway inference THRB AR PPARA... TGFB1 Chemical Gene Pathway Metabolism Pathway in cancer PPAR signaling pathway.
Example chemical-disease inference networks with similar …
WebAug 28, 2024 · 关键基因分析(CTD数据库) 复现工具 ... 疾病的大分类 Filter 我们在网页中 直接搜寻关键字 Atrial 就可以显示该疾病 进一步查看该基因的inference score为23.24 回头看图a FHL2所对应的值就是23.24 接下来同理可得其他关键基因的inference score 然后就可 … WebJan 18, 2024 · 写在前面. DISEASES 每周更新,它集成了来自自动文本挖掘、手工整理的文献、癌症突变数据和全基因组关联研究的疾病基因关联证据。. 可以根据基因(疾病)名称,查询到相关的疾病(基因)。. 并且有相应的文献链接。. 有的数据来自其他数据库,有的 … flow letters
Prediction of new drug indications based on clinical data and …
WebJun 15, 2015 · For CTD, most of the identified 57 disease terms were low-scoring associations that the average number of genes used for each inference is only 1.12. While 5 and 2 terms from CTD analysis were consistent with the previously reported adverse and therapeutic effects, respectively, it is difficult to experimentally validate the results without ... http://ctdbase.org/help/chemDiseaseDetailHelp.jsp WebNov 7, 2012 · B) Diagrams showing three methods to score inferences. The first, CXY and p1, is based on the number of genes (circles) used to make the inference and the … green chargers for table