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Otoferlin抗体

WebNov 7, 2016 · Share. Mutations in the otoferlin ( OTOF) gene lead to profound hearing loss in humans. Interestingly, a number of missense otoferlin mutations cause hearing defects but only at higher body temperature, and the reasons for this have been elusive until now. A study published in this issue of The EMBO Journal (Strenzke et al, 2016) adds insight ... WebOtoferlin is a multi-C2 domain protein associated with genetic human deafness. It functions in hair-cell exocytosis. Several otoferlin C2 domains bind to Ca2+, phospholipids, & proteins. Review. OTOF and PJVK gene variants have a role in auditory neuropathy spectrum disorder in Chinese patients

Otoferlin 抗体 - antibodies-online.cn

WebAnti-Otoferlin Antibody (C-12) is a mouse monoclonal IgG 1 κ Otoferlin antibody, cited in 1 publications, provided at 200 µg/ml. raised against amino acids 691-840 mapping within … WebOtoferlin (PE) Alternative Names (click to expand) Anti Deafness antibody, Anti autosomal recessive 9 antibody, Anti DFNB9 antibody, Anti AUNB1 antibody, Anti Fer 1 like protein 2 … lost ark vern powerpass ticket https://rollingidols.com

汉腾速递 生物医药市场一周资讯（4.1-4.7） - 雪球

WebOtoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has three C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, … WebSeveral otoferlin C2 domains bind to Ca2+, phospholipids, and proteins. Current research reveals requirements for otoferlin in priming and fusion of synaptic vesicles during sound … Web抗Otoferlin抗体(C-12)在各种科学出版物中有2篇引文。 针对哺乳动物靶标蛋白的一抗，如抗Otoferlin 抗体 (C-12)，推荐用于检测一系列哺乳动物物种，主要有小鼠，大鼠和人物种。 … hormones after bariatric surgery

9381 - Gene ResultOTOF otoferlin [ (human)] - National Center for ...

Category:Otoferlin蛋白与听毛细胞突触传导＊_参考网

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Otoferlin抗体

9381 - Gene ResultOTOF otoferlin [ (human)] - National Center for ...

WebOtoraplin 抗体. The protein encoded by this gene is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. This gene is a member of the melanoma-inhibiting activity gene ... WebImmunogen: Anti-RFP monoclonal antibody is a Red Fluorescent Protein (RFP) fusion protein corresponding to the full length amino acid sequence (234aa) derived from the mushroom polyp coral Discosoma. Physical State: Liquid (sterile filtered) Concentration: 1.02 mg/ml by UV absorbance at 280 nm.

Otoferlin抗体

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WebApr 11, 2024 · 汉腾速递 生物医药市场一周资讯（4.1-4.7）. 4月7日，毕马威中国发布第二届生物科技创新50企业榜单，并在毕马威北京、上海、深圳三地办公室，线上线下同步举行颁奖典礼。. 汉腾生物凭借出色的持续创新能力和强劲的市场发展潜能，历经毕马威中国及业界 … Web人Otoferlin(OTOF)ELISA试剂盒分为2种规格，96孔和48孔。 ... 双抗体夹心法：用纯化的抗体包被微孔板，制成固相抗体，往包被有固相抗体的微孔中依次加入标准品或受检样本、生物素化抗体、HRP标记的亲和素，经过彻底洗涤后用底物TMB显色。

Web抗体轻链的Ig结构域示意图. 抗体的轻链包含2个Ig结构域，分别为V domain（VL）和C domain（CL）。每个Ig结构域都由两层β折叠（每层包含3~5股的β链）构成，上图的黄、绿、蓝和红色分别代表一层β折叠，可以按照颜色对应β折叠在抗体的位置。 Webdeafness. We show that otoferlin expression in the hair cells correlates with afferent synapto-genesis and find that otoferlin localizes to ribbon-associated synaptic vesicles. Otoferlin binds Ca2+ and displays Ca2+-dependent inter-actions with the SNARE proteins syntaxin1 and SNAP25. Otoferlin deficient mice (Otof /) are profoundly deaf.

WebOtoferlin might be involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Mutations in the gene for Otoferlin are a cause of neurosensory nonsyndromic … WebOtoferlin CRISPR Knockout と Activation 製品(h) はヒトの遺伝子発現をノックアウトまたはアップレギュレートするように設計された遺伝子編集システムを直接に使用できます。Otoferlin. ... モノクローナル抗体 ...

WebOtoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of …

WebOTOF. 全名. otoferlin. 背景介绍. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has 3 … lost ark veteran insect hunter locationWebサンタクルスバイオテクノロジー社からotoferlin抗体を購入します。モノクローナル抗体はほとんどのタンパク質免疫原に ... lost ark vista in shushirelost ark vista locations saland hillWeb公开资料显示，imc002是易慕峰自主研发的一款基于高特异性vhh纳米抗体靶向cldn18.2的car-t产品，fda已于今年3月批准了该产品的ind申请。 中源协和宣布，旗下全资子公司光谷中源药业研发的vum02注射液临床试验在中国获批，拟用于治疗特发性肺纤维化。 lost ark virtual machineWebOtoferlin 抗体. (Otoferlin (OTOF)) Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has 3 C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has 6 C2 domains. hormones alter cellular operations byWebMyoferlin (MYOF), initially identified in muscle cells, is a member of the Ferlin family involved in membrane fusion, membrane repair, and membrane trafficking. Dysfunction of this … lost ark voice of the forest useWebApr 9, 2024 · 公开资料显示，imc002是易慕峰自主研发的一款基于高特异性vhh纳米抗体靶向cldn18.2的car-t产品，fda已于今年3月批准了该产品的ind申请。 中源协和宣布，旗下全资子公司光谷中源药业研发的vum02注射液临床试验在中国获批，拟用于治疗特发性肺纤维化。 lost ark vitality potion